Controlling cell-to-cell adhesion to facilitate process optimisation and intensification As presented by our Head of Technology at Advanced Therapies London in 2025, this poster provides an overview of the transformative benefits of AggreGuard on microcarrier-based cultures. Download Now
AggreGuard™ boosts viral titre Cell culture homogeneity improves when using AggreGuard (AG), leading to increased viral titre in a Vero cells eGFP-AAV model. Download Now
Continuase™: Empowering continuous cell manufacturing on multiple technology platforms for different scaling strategies In this case study CellRev demonstrates how Continuase™, a proprietary media additive, is capable of controlling cell-to-surface attachment. Continuase™ was used to develop a first of its kind continuous biomanufacturing process on different bioreactors to showcase clear techno-economic advantages for the emerging …
Case Study: Continuase empowering continuous processing Read More »
AggreGuard: Transforming process efficiency one supplement at a time. As presented by our Head of Technology at ESACT UK in 2025, this poster provides an overview of the transformative effects of AggreGuard on microcarrier-based cultures. Download Now
AggreGuard™: VERO cells case study The reported findings highlight the potential to improve VERO upstream bioprocessing efficiency for existing batch/fed-batch modes using AggreGuard™. Experimental design considerations: Cell type and microcarrier (MC) selection screens (if data is unknown). AggreGuard™ time-dose response screening in multi-well plates to evaluate cell type (i.e., extracellular matrix composition, attachment behaviour, doubling …
Our flagship media additive, AggreGuard, reduces cell-to-cell aggregation in microcarrier-based cell cultures. Available in Research and GMP grades, AggreGuard gently digests the extracellular matrix components to prevent cell-to-cell adhesion, without affecting cell-to-surface attachment, to increase process productivity. Compatible with all commercially available microcarriers and adherent cell lines. Download the AggreGuard product brochure and FAQs to …
We assess the impact of our media additive, AggreGuard, on cell-to-cell mediated microcarrier aggregation for VERO cells grown on Kuraray’s Scapova CL PVA microcarriers. Designed to increase cell viability and eliminate processing bottlenecks, AggreGuard controls and reduces cell-to-cell attachment without affecting cell-to-surface attachment. In this study, we put AggreGuard to the test to determine its …
App Notes: AggreGuard & Kuraray Scapova CL PVA Microcarriers Read More »
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